Your dog's friendly behaviour is thanks to a genetic tweak

A new study reveals that chromatin's 3D structure significantly influences the evolution of social behavior in dogs

A new study reveals that chromatin's 3D structure significantly influences the evolution of social behavior in dogs

Researchers focused on the GTF21 gene, which is associated with hypersociability in humans and found differences in its variants between wolves and dogs.

The team used brain tissue samples from dogs to study how these genetic variants affect the 3D structure of DNA.

They discovered that ancient and modern variants of the GTF21 gene influence chromatin loop formation differently, affecting gene expression.

The findings suggest molecular parallels between dog sociability and human Williams-Beuren syndrome, emphasizing the evolutionary significance of these genetic changes

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