A recent study reveals gut bacteria may cause eczema, asthma, food allergies, and hay fever in youngsters.
Diet, birth, environment, and antibiotic exposure can affect the infant’s gut flora.
Antibiotics may kill sensitive microorganisms, while nursing feeds and replenishes gut flora.
Paediatrics Professor Stuart Turvey of the University of British Columbia, said, “We’re seeing more and more children and families seeking emergency department help due to allergies.Understanding why and how to avoid allergies affects hundreds of millions of children globally.”
The Nature Communications study studied how these variables altered gut microbial balance and the development of these allergies, which affect over a third of the globe.
The study investigated clinical assessments from 1,115 children followed from birth to age five.
Over half (592) of the children were diagnosed with one or more allergy illnesses by an experienced physician, whereas 523 had no allergies at any time.
Stool samples from clinical visits at three months and one year old were used to assess the children’s microbiomes.
The stool samples showed a bacterial signature linked to any of the four allergens by age five.
The bacterial profile indicates dysbiosis, or an unbalanced gut microbiota, which may have caused intestinal lining damage and increased gut inflammation.
Because of their numerous health benefits, our systems tolerate millions of gut bacteria. Keeping a tight barrier between them and our immune cells and restricting inflammatory signals that might activate them help us tolerate them “UBC doctoral candidate Courtney Hoskinson said.
“We found a common breakdown in these mechanisms in babies before allergies,” she said.
The findings may help anticipate and avoid allergies in children.
Turvey added, “Developing therapies that change these interactions during infancy may prevent all sorts of allergic diseases in childhood, which often last a lifetime.”
Conclusion:-
A study by Nature Communications suggests that gut bacteria may cause eczema, asthma, food allergies, and hay fever in children. Factors such as diet, birth, environment, and antibiotic exposure can affect the infant’s gut flora. Antibiotics may kill sensitive microorganisms, while nursing feeds and replenishes the gut flora. Over a third of children worldwide suffer from allergies, and understanding their causes and prevention is crucial. The study examined clinical assessments from 1,115 children aged three months to five years old. Over half of the children were diagnosed with one or more allergy illnesses, while 523 had no allergies at any time. The stool samples showed a bacterial signature linked to any of the four allergens by age five, indicating dysbiosis or an unbalanced gut microbiota. The findings may help anticipate and avoid allergies in children, and developing therapies that change these interactions during infancy may prevent allergic diseases in childhood, which often last a lifetime.
