New liver cancer treatment: Scientists use microrobots in MRI device

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A new liver cancer treatment uses magnet-guided microrobots in an MRI device. The microrobots, made of iron oxide nanoparticles, can provide targeted medical treatment.

Canadian researchers used magnet-guided microrobots in an MRI system to treat liver cancer. Researchers say small biocompatible iron oxide nanoparticle robots guided by a magnetic field could deliver focused medical treatment.

They noted that these microrobots’ gravity surpasses their magnetic force, limiting their direction when the tumour is higher than the injection site.

“To solve this problem, we developed an algorithm that determines the patient’s body position for a clinical MRI to take advantage of gravity and the magnetic navigation force,” stated University of Montreal researcher Gilles Soulez.

“This helps microrobots reach tumor-feeding artery branches. We can precisely guide them to treatment places and preserve healthy cells by adjusting the magnetic field “Gilles said.

MRI is a non-invasive imaging technique that provides three-dimensional anatomical images.

The novel approach, described in Science Robotics, may transform liver cancer interventional radiology, researchers claimed.

Hepatocellular carcinoma, the most frequent, kills seven lakh people worldwide and is usually treated with transarterial chemoembolization, they said.

The researchers say this invasive treatment includes injecting chemotherapy directly into the liver tumour’s artery and limiting its blood supply with microcatheters guided by X-ray. Highly qualified staff are needed.

An implanted chemotherapeutic catheter can be utilized for magnetic resonance navigation. Other benefits include improved tumor visualization on MRI than X-rays “explained Soulez.

The scientists assembled “particle trains,” magnetisable microrobot aggregates, using an MRI-compatible microrobot injector. These are easier to pilot and identify on MRI images due to their higher magnetic force. In this way, the researchers can confirm the train is on the right track and the treatment dose is sufficient.

Soulez said, “We carried out trials on 12 pigs in order to replicate, as closely as possible, the patient’s anatomical conditions. This proved conclusive: the microrobots preferentially navigated the branches of the hepatic (liver) artery which were targeted by the algorithm and reached their destination.”

Conclusion

New liver cancer treatment uses magnet-guided microrobots in an MRI system from Canadian researchers. Iron oxide nanoparticle microrobots can target medical treatment. The researchers created an algorithm to steer microrobots to tumor-feeding artery branches using gravity and magnetic force. Interventional radiology for liver cancer may evolve.

“Introducing OpenAI Sora: Text to Video in 60 Seconds!”

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Sora, a futuristic AI created by OpenAI, the company behind ChatGPT. Short videos can be made using only words, which is quite impressive. Their aim is to aid AI in comprehending the world more effectively, thereby helping us address issues. OpenAI CEO Sam Altman posed Sora on his social media account. Sora’s videos were a result of the ideas he received from people. One more person uploaded a Sora video that appeared very genuine.

Videos produced by Sora can offer a wealth of information, such as moving images and vivid backgrounds. It’s savvy and capable of performing its tasks. The potential consequences of using this technology incorrectly are a source of concern for some. YouTuber Marques Brownlee expressed concern about our use and caution.

The safety issue is being addressed by OpenAI, as per their statement. To avoid any complications, they are conducting extensive testing on Sora. Tools are being developed to detect fake videos created by Sora. Before releasing Sora to the public, they’re receiving feedback from different individuals to improve and make it safer.

Sora is currently unavailable for most people to check for issues. To enhance its performance, OpenAI is seeking input from artists and filmmakers. They’re exhibiting their early progress to showcase the potential of AI and seek assistance in improving it. They are of the opinion that feedback can enhance future AI safety and functionality.

‘Sangam: Digital Twin’ – Government invites EOIs for future infrastructure planning and design

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The Indian government’s ‘Sangam: Digital Twin’ initiative has invited Expressions of Interest (EOIs) to reshape infrastructure planning and design using 5G, and other modern technologies. The submission date is March 15, 2024.

The Indian government has launched the ‘Sangam: Digital Twin’ initiative, encouraging industry leaders, innovators, MSMEs, startups, academia, and forward-thinkers to submit EoIs. The Department of Telecommunications (DoT) effort combines 5G, IoT, AR/VR, AI, AI native 6G, ‘Digital Twin’ and next-generation computational technologies to reshape infrastructure planning and design.

March 15, 2024, is the deadline to submit EoIs.

The ‘Digital Twin’ technology creates virtual replicas of actual assets for real-time monitoring, simulation, and analysis for experimental iterations and feedback loops to optimize results.

DoT has encouraged industry pioneers, startups, MSMEs, academia, innovators, and forward-thinkers to pre-register and actively participate in Sangam’s outreach programs “and explore, create, and commit to transform the future of infrastructure planning and design.”

The first step is exploratory for horizon clarity and creative potential unleashing. The second stage involves practical demonstration of specific use cases to create a blueprint for scaling and replicating successful tactics in future infrastructure projects through collaboration, said DoT.

The ‘Digital Twin’ technology lets businesses, services, and customers connect seamlessly online.

The Survey of India (SOI) and Indian private mapping company Genesys International signed a deal last November to create 3D maps of urban landscapes and physical assets with precise details, aligning with the national geospatial policy’s goal of creating ‘Digital Twins’ of major cities and towns by 2035.

Conclusion

The Indian government is seeking Expressions of Interest from industry leaders, innovators, MSMEs, startups, academia, and forward-thinkers for the ‘Sangam: Digital Twin’ initiative. The program uses 5G, IoT, AR/VR, AI, AI native 6G, and next-generation computing technologies to rethink infrastructure planning and design. The submission date is March 15, 2024. For experimental iterations, ‘Digital Twin’ technology allows real-time monitoring, simulation, and analysis. The effort supports the national geospatial policy’s 2035 aim of creating ‘Digital Twins’ of major cities and towns.

Where Are They Now? Explaining the Absence of First Farmers’ Protest Leaders in Round Two

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Leading agricultural figures, who spearheaded the farmers’ demonstration in 2020–21, have disassociated themselves from the uproar this year. For the last three days, the non-political Samyukta Kisan Morcha, which was reorganised from the previous Samyukta Kisan Morcha, has been demonstrating throughout Punjab and Haryana in an effort to spark the Farmers’ Protest 2.0.

The ‘Delhi Chalo’ march was also demanded by the farmers’ associations. In contrast to the last upheaval, the following names are absent from SKM’s “Delhi Chalo” call this year:

  • Yogender Yadav
  • Joginder Singh Ugrahan
  • Tikait, Rakesh
  • Gurnam Singh The Chaduni
  • Balbir Singh Rajinder
  • Dr. Darshan Pal, Manjit Rai
  • Kumar Shiv Kakka
  • Singh, Dr. VM

Government-Farmer Discussions 

There have been two fruitless efforts at communication between farmers and the administration amid the ongoing demonstrations.

Despite the government’s stated readiness to engage in negotiations with farmer associations, the two rounds of talks have yielded no clear results.

The following round of negotiations is now scheduled on Sunday, February 18.

AGREEABLE DEMANDS OF THE FARMERS

A minimum support price (MSP) for crops, loan waivers, the dismissal of lawsuits against the farmers, and changes to the Essential Commodities Act are among the requests being made by the farmers’ continuous protest.

Farmer leaders have, however, also made a number of additional requests, including the cancellation of the WTO agreement pertaining to farmers, the rejection of the power Amendment Bill 2020, the continuation of farmers’ exemption from environmental rules, and opposition to the installation of electronic power metres.

The government has been presented with the following demands by farmer organisations:

  • Endorsing legislation ensuring MSP and offering MSP resources for all crops
  • Releasing agricultural workers’ and farmers’ debts and giving them a 10,000 rupee monthly pension
  • Removing the Land Acquisition Act of 2013 and guaranteeing 200 days of work under MGNREGA every year
  • Giving government jobs and compensation to the families of farmers who were slain during the protest; raising the daily pay to Rs 700
  • Ensuring that individuals accountable for the Lakhimpur Kheri tragedy get punished
  • Passing legislation that punishes firms who manufacture counterfeit fertilisers and pesticides
  • Rescinding the Electricity Amendment Bill 2020 and doing away with Punjabi farmers’ requirement to install electronic metres
  • Establishing a National Spice Commission
  • Avoiding following pollution laws on farmers
  • Establishing agricultural prices in accordance with the Swaminathan Commission report’s recommendations
  • Prohibiting free trade deals

According to reports, the ‘Delhi Chalo’ march is being attended by about 200 farmer associations. Still, even Punjabi small-scale farmer associations joined it.

Remarkably, there are only about 40 farmer associations in Punjab; in contrast, there were about 500 farmer organisations that participated in 2020–21.

Jaya Bachchan nominated for 5th term in Rajya Sabha; Know her and Amitabh Bachhan’s combined wealth

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Jaya Bachchan has been nominated for a fifth term in the Rajya Sabha by the Samajwadi Party. Jaya also reported her and Amitabh Bachchan’s personal assets for 2022-23.

Actress-turned-politician Jaya Bachchan has been nominated by the Samajwadi Party (SP) for a fifth successive term in the Rajya Sabha. . On Thursday, Jaya declared her and her husband Amitabh Bachchan’s personal assets in an election affidavit. Jaya Bachchan listed her and her husband’s 2022-23 moveable and immovable property values in the election affidavit.

Jaya Bachchan reported a 2022-23 net worth of Rs 1.63 crore. In the same financial year, Amitabh Bachchan’s affidavit listed Rs 273.74 crore in total assets. The affidavit stated Jaya’s bank balance as Rs 10.11 crore and Amitabh’s as Rs 120.45 crore. Their movable assets total Rs 849.11 crore and their immovable assets Rs 729.77 crore.

The electoral affidavit states that Jaya owns Rs 40.97 crore in jewelry and a Rs 9.82 lakh automobile. Amitabh has Rs 54.77 crore in jewelry and Rs 17.66 crore in automobiles, including two Mercedes and a Range Rover.

Their shared assets come from diverse sources, according to the election document. Jaya’s wealth comes from advertising, MP pay, and acting fees. In addition to acting fees, Amitabh earns interest, rent, dividends, capital gains, and solar plant earnings.

Jaya Bachchan last appeared in Karan Johar’s Rocky Aur Rani Kii Prem Kahaani with Ranveer Singh and Alia Bhatt.

Amitabh Bachchan last appeared in Tiger Shroff’s Ganapath. The reality show Kaun Banega Crorepati ended lately.

Conclusion

The Samajwadi Party nominated Jaya Bachchan for a sixth Rajya Sabha term. She and her husband Amitabh Bachchan presented an election affidavit stating their 2022-23 net worth. Their movable assets total Rs 849.11 crore and their immovable assets Rs 729.77 crore. Jaya makes money from ads, her MP pay, and acting fees, whereas Amitabh makes money from interest, rent, dividends, capital gains, and solar plant earnings.

Hyderabad Authorities Raid 7 Premises in Forex Violation Inquiry, Seize Rs 78 Lakh

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Under the terms of the Foreign Exchange Management Act (FEMA), 1999, the Enforcement Directorate searched seven sites in and around Hyderabad that were connected to the Kings Group of enterprises and its affiliated organisations on Tuesday.

Based on information that the Kings Group of companies, represented by Mohammed Shahnawaz and Mohammed Zubairuddin, along with other individual entities, had made a number of foreign investments, including ones in the UK and the UAE, in violation of FEMA provisions, the probe agency launched an investigation.

Information also suggested that they were using the hawala network to transact illicit foreign currency. Digital gadgets, unaccounted cash totalling Rs 76.5 lakh, and foreign currency worth about Rs 1.5 lakh were seized as a result of ED searches. Additionally, incriminating records proving international bank accounts, affiliations with foreign organisations, and foreign investments were found.

More study is now being researched.

Government excludes Paytm Payments Bank from list of 32 banks for buying Fastags

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India’s road toll authority’s ban on Paytm Payments Bank buying Fastags affects around 20 million users. Paytm is facing challenges in business and monetization.

Paytm Payments Bank has been excluded from a list of 32 banks for buying Fastags. The Indian road toll authority doesn’t approve Paytm Payments Bank for buying Fastags.

This move will require RFID stickers for around 20 million Paytm Fastag users. Airtel Payments Bank, Axis Bank, HDFC Bank, ICICI Bank, State Bank of India, and others are Fastags-authorized.

After central bank regulations, Paytm may struggle to thrive. Macquarie Group analysts said RBI limits risk Paytm’s business model and monetization. Over the previous 11 days, Paytm has lost Rs 27,000 crore, or 57% of its value.

The removal of Fastags from the permitted banks list adds to Paytm’s regulatory issues and struggle to retain consumers in a changing sector.

Conclusion

India’s road toll authority doesn’t approve Paytm Payments Bank for buying Fastags. This move requires new RFID stickers for around 20 million Paytm Fastag subscribers. Paytm faces RBI rules and a sharp reduction in value.

Health experts advise against using Rice Bran Oil; Know why

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Contaminants found in refined palm oil, palm olein oil, vegetable oils, and marine oils can cause cancer. According to health experts, we should avoid cooking oils with cancer-causing chemicals that are present even in refined rice bran oil, that is otherwise considered healthy.

Health experts have advised against using cooking oils with glycidyl esters (GE) and 3-monochloropropane-1,2-diol esters. These pollutants threaten food and oil refineries worldwide.

When edible oils are heated to remove unwanted tastes, colors, and aromas during industrial refining, GE and 3-MCPD can form. While refined palm oil and palm olein oil have the highest concentrations, other refined vegetable oils (safflower, coconut, sunflower, rice bran oil, soybean oil, etc.) and refined marine oils (fish oils) also include these pollutants. When consumed in high amounts, the side effects of rice bran oil might be harmful to health. Rice bran oil contains omega-6-fatty acids that may cause cancer. In addition, it might lower blood calcium levels. It might also cause flatulence, gas, and stomach discomfort.

Health experts say the refined vegetable and marine oils release unwanted chemical compounds into food when deep fried, baked, grilled, or roasted, increasing health concerns.

Experts urge Indian health officials to set limitations like Europe’s as cancer incidence climb. Studies show that excessive GE and 3-MCPD consumption damages kidneys and male reproductive organs.

Doctor Rahul Bhargava, Principal Director of Hematology and Bone Marrow Transplant at Fortis Memorial Research Institute, Gurugram, emphasized the need to address carcinogenic chemicals like GE and 3-MCPD in cooking oils. Media reported, “GE and 3-MCPD in cooking oils must be addressed because to rising cancer rates. As oil pollutants can cause cancer over time.”

“With the rising cancer rate in India and extensive usage of cooking oils, government entities and FSSAI should implement these regulations. Dr. Rahul Bhargava noted that label compliance with GE and 3-MCPD limitations empowers customers to choose healthier and safer cooking oils.

Dr. Sushila Kataria, Director of Internal Medicine at Medanta, Gurugram, warned that GE and 3-MCPD pollutants in cooking oils can cause kidney damage and cancer. She stressed that Indian governments must regulate and reduce these pollutants in cooking oil to protect public health.

We must raise awareness of the health concerns of GE and 3-MCPD in cooking oils. GE and 3-MCPD can cause renal damage and cancer. Indian government laws should also reduce these pollutants in cooking oil. She advised picking cooking oils that meet EU safety standards of 3 MCPD & GE for health.

While India has made progress in controlling trans fats, there has been limited action in formulating guidelines for GE and 3-MCPD. To guarantee safer cooking oil usage, experts advise India to follow EFSA guidelines on these pollutants.

Conclusion

Health experts are urging India to set limits on cooking oils containing harmful substances like glycidyl esters (GE) and 3-monochloropropane-1,2-diol esters (3-MCPD), which can cause cancer in the long term. These pollutants can form in edible oils during industrial refining, harming food and oil refineries globally. The high concentrations of these contaminants in refined palm oil and palm olein oil, as well as other refined vegetable and marine oils, can lead to increased health risks when used in cooking methods like deep frying, baking, grilling, or roasting. Experts advise Indian health officials to adopt European norms as cancer incidence rise. Consumers must follow GE and 3-MCPD label limitations to choose healthier cooking oils.

Over 5.14 billion cyberattacks made on Indian apps and websites

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Over 5.14 billion cyberattacks hit Indian websites and apps last year. Indian software-as-a-service organizations were targeted for high-value client data.

A recent survey said Indian websites and apps saw over 5.14 billion cyberattacks last year, primarily in healthcare. A 10 times surge in attacks made Indian software-as-a-service (SaaS) companies prime targets for cybercriminals due to their high-value consumer data.

Indusface, a TCGF II (Tata Capital)-funded application security business, found that carding attacks predominantly targeted retail and e-commerce.

Manufacturing, telecommunications, IT services and consulting, marketing, and advertising are also examined.

“Bot-driven, low-rate Distributed Denial of Service (DDoS) attacks increased along with card cracking and credential stuffing,” stated Indusface CEO Ashish Tandon.

On mitigation, he said, “We have seen reasonable success where AI models alert our managed services team of possible anomalies and the team can quickly take mitigation measures.”

Indusface’s ‘AppTrana’ network stopped 6.8 billion global threats, 5.14 billion of which targeted Indian businesses, SMEs, and governments.

A 63% quarterly increase in cyberattacks from Q1 to Q4 in 2023 highlights the need for strong cybersecurity, the research added.

The analysis highlights the vulnerability of many businesses, including healthcare, where 100% of websites were attacked by bots, and banking, finance, and insurance, where 90% were attacked.

Eight out of 10 sites were targeted by bots in 2023, adding 46% per quarter to over 467 million bot attacks.

Apart from India, the survey listed the US, UK, Russia, Germany, and Singapore as major cyber attack origins.

Conclusion

Over 5.14 billion cyberattacks hit Indian websites and apps last year, with healthcare being the most targeted. SaaS companies in India were targeted for their high-value consumer data. Retail and e-commerce were mainly targeted by carding assaults. Indusface’s ‘AppTrana’ network prevented 6.8 billion global threats, 5.14 billion targeting Indian businesses, SMEs, and governments. In 2023, cyberattacks rose 63% from Q1 to Q4, emphasizing the necessity for strong cybersecurity.

Rahul Gandhi and Tejashwi Yadav Lead Bihar Tour in Jeep, Yadav Takes Driver’s Seat

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During the yatra, Rahul Gandhi drives a jeep through Bihar, with Tejashwi Yadav at the wheel.

On Friday, in Sasaram, Bihar, Rahul Gandhi and former deputy chief minister Tejashwi Yadav embarked on his ‘Bharat Jodo Nyay Yatra’. The Yatra is expected to visit Uttar Pradesh later today after reaching its conclusion in Bihar.

Rahul Gandhi and other politicians were observed being driven by Mr. Yadav in the lead vehicle during the yatra’s passage through Sasaram; the RJD leader acknowledged his comrade in a post on Facebook.

Additionally, Mr. Yadav and Rahul Gandhi will share the platform at a public gathering in Kaimur in Dhaneychha, located in the Durgawati district of Kaimur.

Since state Chief Minister Nitish Kumar abandoned his links with the INDIA alliance, this would be the first time the RJD leader appears on the same stage as Mr. Gandhi in Bihar.